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Darin K Edwards Selected Research

2019-nCoV Vaccine mRNA-1273

5/2024Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines.
1/2023Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2.
1/2023Original SARS-CoV-2 monovalent and Omicron BA.4/BA.5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results.
11/2022Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2.
11/2022Safety, immunogenicity and antibody persistence of a bivalent Beta-containing booster vaccine against COVID-19: a phase 2/3 trial.
10/2022A Bivalent Omicron-Containing Booster Vaccine against Covid-19.
3/2022Safety and Immunogenicity of a 100 μg mRNA-1273 Vaccine Booster for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
2/2022Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice.
1/2022Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice.
1/2022mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2.
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Darin K Edwards Research Topics

Disease

21COVID-19
02/2024 - 10/2020
16Infections
05/2024 - 05/2021
6Inflammation (Inflammations)
01/2023 - 10/2020
4Breakthrough Infections
02/2022 - 08/2021
4Weight Loss (Weight Reduction)
02/2022 - 08/2021
2Severe Acute Respiratory Syndrome
03/2022 - 10/2021
2Pneumonia (Pneumonitis)
02/2022 - 08/2021
2Human Influenza (Influenza)
01/2022 - 01/2017
1Virus Diseases (Viral Diseases)
01/2023
1Communicable Diseases (Infectious Diseases)
01/2022
1Acute Lung Injury
10/2021
1Persistent Infection
01/2021

Drug/Important Bio-Agent (IBA)

25VaccinesIBA
05/2024 - 01/2017
192019-nCoV Vaccine mRNA-1273IBA
05/2024 - 10/2020
10mRNA VaccinesIBA
01/2024 - 01/2017
7Messenger RNA (mRNA)IBA
01/2024 - 01/2017
5Neutralizing AntibodiesIBA
11/2022 - 10/2020
3COVID-19 VaccinesIBA
05/2024 - 10/2021
3Proteins (Proteins, Gene)FDA Link
01/2024 - 02/2022
3AntibodiesIBA
01/2023 - 10/2021
2IgG Receptors (Fc gamma RI)IBA
01/2023 - 11/2022
2Combined VaccinesIBA
11/2022 - 09/2022
2N-(2-cyanoethylene)urea (BA 1)IBA
10/2022 - 01/2022
2Viral AntigensIBA
05/2021 - 01/2021
1Broadly Neutralizing AntibodiesIBA
05/2024
1Interleukin-10 (Interleukin 10)IBA
01/2024
1mRNA-1273.214 COVID-19 vaccineIBA
10/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Influenza Vaccines (Influenza Vaccine)FDA Link
01/2022
1N-methyl-valyl-amiclenomycin (BA 2)IBA
01/2022
1CytokinesIBA
01/2022
1Ad26COVS1IBA
01/2022
1aluminum sulfate (alum)IBA
10/2021
1Protein Subunit VaccinesIBA
10/2021
1AntigensIBA
10/2020
1Hemagglutinins (Hemagglutinin)IBA
01/2017